Migraine and the Hormone Connection

Presented by Dr Wayne Elphinstone DC. DACNB

Date: 5th December, 2026 Time: 10:00 AM - 1pm BST

If you have been told that hormonal migraines are simply bad luck, an unavoidable side effect of your cycle, or something to suppress with painkillers in a dark room, you have been given an incomplete story.

A hormonal migraine is not just a reproductive symptom. It is a complex neurovascular event driven by the direct crosstalk between fluctuating endocrine signals, brainstem sensitivity, and cellular energy failure.

On Saturday, 5th December 2026 (10:00 AM – 1:00 PM BST), join us for a comprehensive, 3-hour masterclass dedicated to uncovering the exact neuro-endocrinology behind hormonal migraine and the evidence-based strategies required to resolve it.

What We Will Break Down:

  • The Neuroendocrine Circuitry: Exactly how rapid drops in oestradiol (the primary active form of oestrogen) and progesterone directly trigger the Trigeminovascular System (TVS)—the main sensory network responsible for cranial pain transmission.

  • Neuropeptides & Cortical Sensitivity: The precise mechanisms by which hormonal shifts upregulate Calcitonin Gene-Related Peptide (CGRP)—a potent inflammatory neuropeptide and vasodilator—and alter the balance between Glutamate (excitation) and GABA (gamma-aminobutyric acid, inhibition), lowering the threshold for migraine attacks.

  • The HPA Axis: How chronic stress via the Hypothalamic-Pituitary-Adrenal (HPA) axis and impaired liver Phase I/II clearance or gut microbiome dysbiosis prevent healthy oestrogen elimination, recycling inflammatory metabolites back into circulation.

  • Metabolic & Functional Solutions: Clinical protocols bridging functional neurology, targeted metabolic interventions, and mitochondrial support to stabilise brain excitability and build neurological resilience.

Webinar Details:

  • Date: Saturday, 5th December 2026

  • Time: 10:00 AM – 1:00 PM BST (3 Hours Live Online)

  • Format: Deep-dive presentation with live clinical Q&A

  • Access: Live stream link provided upon registration (recording access included)

Whether you are a clinician looking to sharpen your diagnostic approach or someone seeking definitive, mechanism-based answers to reclaim your life from chronic pain, this session is built to raise the standard of care.